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Propanediol Caprate – Bridging the Gap between in-vitro and in-vivo Studies in the Development of Deodorant Actives

Sweating can be triggered by many situations in our daily lives, resulting in a strong need for effective solutions to prevent odor formation, ideally combining a high degree of naturalness and skin compatibility. To optimize the development of such products, we have focused on the sweat malodor genesis and explored its complexity with our 3D ex-vivo model. In this report, we have presented both the model and its first output, an effective novel deodorant SymDeo® PMD green (INCI: propanediol caprate) which succeeded the subsequent in-vivo trials.
*This article was published in Personal Care Magazine October 2024: Deodorant actives: bridging the development gap

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Scalp Microbiome and Dandruff – Exploring Novel Biobased Esters

Recent data suggest that dandruff might be associated with dysbiosis of the scalp microbiome. This mini review summarizes the microbiome changes seen with the dandruff condition, as well as different solutions for dandruff control and their effects on the scalp microbiome in relation to in vivo efficacy. Since zinc pyrithione has been banned from cosmetics in the EU, the mediumchain fatty acid ester propanediol caprylate is a new option.
*This article was published in Cosmetics October 2024: Scalp Microbiome and Dandruff - Exploring Novel Biobased Esters

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